chicken coccidiosis vaccine

WIXBIO Chicken Coccidiosis Vaccine

Product Name

Coccidiosis quadrivalent vaccine for chickens, live (strain E. tenella ETGZ, strain E. necatrix ENHZ, strain E. acervulina EAGZ, strain maxima EMPY)

Main compositions and content

Strain eimeria tenella ETGZ 1,700±10% sporulated oocysts/dose

strain eimeria necatrix ENHZ 1,700±10% sporulated oocysts/dose

strain eimeria acervulina EAGZ 1,700±10% sporulated oocysts/dose

strain eimeria maxima EMPY 1,700±10% sporulated oocysts/dose

Characteristics of WIXBIO Coccidiosis Vaccine

The WIXBIO coccidiosis vaccine is a quadrivalent vaccine made from harmful coccidia oocysts found in clinical settings, weakened through a dual attenuation process. It gives chickens a consistent oral dose of oocysts to trigger protective immunity against coccidiosis. It’s highly effective at preventing chicken coccidiosis, with a clinical protection rate of over 90%, and tackles issues like coccidia drug resistance and worries about drug residues in poultry products.

This chicken coccidiosis vaccine offers complete protection with dual-attenuated intermediate strains that boost antigenicity. It causes minimal immune stress, barely affects early growth rates, and provides long-lasting immunity once established. It cuts down on medication costs, overcomes the downsides of drug-based prevention, and lowers feed ratios and farming costs. It’s non-toxic, antibiotic-free, and leaves no drug residues, avoiding food safety risks.

Transportation and Storage of WIXBIO Coccidiosis Vaccine

When transporting the chicken coccidiosis vaccine, pack it in a foam box and keep it away from direct contact with ice using newspaper or foam boards. Store it at 2–8°C—never freeze it or keep it near heat sources during transport or storage.

Determining Vaccination Age for Chicken Flocks

Broilers are usually vaccinated at 1–3 days of age. For chickens slaughtered after 60 days of age—like high-quality Sanhuang chickens, Ma chickens, breeders, and native breeds—vaccinate at 4–6 days of age.

If pullorum disease is severe, treat it with medication first, stop the drugs for 1–2 days, and then vaccinate. Plan to stagger the vaccination with other vaccines by 1 day.

WIXBIO Coccidiosis Vaccine Usage Instructions

Drinking Water Vaccination Method

Drinking water vaccination is an easy way to immunize. Still, since the active part of the chicken coccidiosis vaccine is granular oocysts that sink in water, you need to add a suspension aid during dilution. This keeps the oocysts floating and evenly spread in the water so chickens can take a uniform dose. Using a suspension aid in drinking water makes vaccination more even than dripping it into each chicken’s mouth.

Tools You’ll Need:

Several drinking water containers, one large water tank, two toothpicks, one wooden or bamboo stirring stick, and one measuring cup or spoon.

It can mess with the suspension if your local water is hard (like if it leaves a lot of scale when boiled). Use cold-boiled water to dilute the vaccine instead. The day before vaccinating, figure out how much water you’ll need based on the number of chickens—plan for 6 kg per 1,000 chickens—and prep a tank of cold-boiled water.

WIXBIO Coccidia Vaccine Drinking Water Immunization Specifications
Coccidiosis vaccine name	Specification	Immunization Quantity	Water Volume	Quantity of Coccidia Vaccine	Suspension aid quantity
Chicken Coccidiosis Vaccine	1000pcs/portion	1000 birds/vial	6KG	1 vial	1 bag
Chicken Coccidiosis Vaccine	1000pcs/portion	1000 birds/vial	6KG	1 vial	1 bag
Chicken Coccidiosis Vaccine	1000pcs/portion	1000 birds/vial	6KG	1 vial	1 bag

Steps for Using the Vaccine:

1. Shake the vaccine well, pop the cap, pour it bottle by bottle into the measured water, rinse any leftover vaccine from the bottle into the mix, and blend thoroughly.
2. Shake the suspension aid for at least 5 minutes until the sediment is fully suspended. Open the cap and pour it into the vaccine mix while shaking (to avoid leftover sediment at the bottom). Stir with a wooden stick until mixed well—the suspension aid usually dissolves in about 1 minute. Keep stirring for another 5 minutes to fully combine the vaccine and suspension aid.
3. Add the prepared vaccine mix to the chickens’ drinking water containers.

Feed Mixing Immunization Method

In big, standardized farms with no hands for drinking water vaccination, mixing the vaccine into feed works just as well for immunity.

WIXBIO Coccidiosis vaccine mixing and immunization method
Number of chickens immunized	Feed quantity	Coccidia vaccine	Amount of water	Food Red
10000 birds	40KG	10,000 doses	5KG	2G

1. Measure water, feed, vaccine, and food-grade red dye based on your flock size (e.g., 10,000 chickens). Note: The red dye colors the vaccine solution so you can see if it’s evenly spread in the feed—it’s not a must-have part of the vaccine and can be prepped as needed.
2. Add the measured red dye to the water and mix well.
3. Shake the vaccine thoroughly, pour it bottle by bottle into the red dye solution, rinse any leftover vaccine from the bottle, stir until uniform, and load it into a sprayer.

Feed Mixing Process:

1. Lay a plastic sheet on the ground. Spread 40 kg of feed evenly, about 1–2 cm thick, keeping the thickness consistent.
2. Pressurize the sprayer and spray the vaccine solution onto the feed in a “Z” pattern while shaking it.
3. Once the surface is evenly sprayed, rake the feed to mix it up.
4. Spread the feed out again and repeat steps (2) and (3) twice.
5. Divide the mixed feed into troughs or trays, place them in the chicken house for the chickens to eat, and switch to regular feed once the mix is gone.

Notes:

1. From 1 day before the first dose to 1 week after the third, don’t use drugs with anti-coccidial effects in clinical production—it’ll mess up the immunity.
2. Make sure feed mixing and feeding stay relatively uniform.
3. No need to limit feed.

Medication and Precautions During WIXBIO Coccidiosis Vaccine Use

1. Feed-Specific Guidelines

Here’s a rundown of drugs to avoid in feed: Don’t add anything with anti-coccidial effects, like salinomycin, tylosin, decoquinate, kanamycin, nicarbazin, maduramicin, sulfonamides, clopidol, arsanilic acid, furans, penicillins, or plant essential oils. For the first 25 days, also skip tetracyclines (like doxycycline, chlortetracycline, oxytetracycline), organic arsenic stuff (like arsanilic acid, roxarsone), and any specialized anti-coccidial drugs.

2. Clinical Medication

Don’t use drugs with anti-coccidial activity during treatment—it’ll interrupt immunity. (The figure below shows banned medicines and timelines for a first dose at 6 days.)

• Anti-coccidial drugs: Methyl salinomycin, kanamycin, tylosin, nicarbazin, decoquinate, maduramicin, etc.
• Sulfonamides: Sulfadiazine sodium, sulfachloropyrazine, sulfamethoxypyridazine, etc.
• Tetracyclines: Doxycycline, chlortetracycline, oxytetracycline, tetracycline, etc.
• Chloramphenicol: Florfenicol
• Synergists and others: TMP, roxarsone
• Penicillins: Penicillin
• Plant essential oils: Oregano oil, artemisinin, etc.

3. Medication During Vaccination

There are limits on meds during vaccination, but don’t overdo it and avoid treating problems, as that can harm your health. For example:

• If chicks have destructive pullorum disease, treat it first, stop meds for 1 day, then vaccinate.
• Skip doxycycline for breathing issues from insulation or vaccine stress, but try tylosin, roxithromycin, or tilmicosin.
• For gut problems, avoid florfenicol or oxytetracycline hydrochloride, but use quinolones, probiotics, Enterococcus faecalis, or Clostridium butyricum.

4. Pre-Immunization Prep

There is no need to limit feed or water before vaccinating. Keep the water flowing normally to help chickens eat at the same time and get even immunity.

5. Transportation and Storage of Chicken Coccidiosis Vaccine

Pack the vaccine in a foam box for transport, keeping it away from ice with newspaper or similar materials. Store it at 2–8°C—don’t freeze it or let it near heat sources during transport or storage.

Key Points for WIXBIO Coccidiosis Vaccine Immunization Management

Even dosing, pen expansion and litter management are what make it work during vaccination.

1. Ensure Even Vaccination Dosing

Even dosing for the first shot gives all chickens the same baseline immunity and similar oocyst shedding. Spread oocysts evenly across the chicken house corners in floor rearing to set up consistent reinfection. Uneven dosing means oocyst spread in the litter worsens after reproduction—too many oocysts can hit unvaccinated or under-dosed chickens hard, causing strong reactions since they lack baseline immunity.

2. Boost Pen Expansion and Litter Management

Expand pens based on the breed’s rearing needs.

In floor rearing, expanding daily or every other day leaves fewer oocysts in new areas and new litter, while old litter has more, leading to uneven reinfection. Chickens overeating react strongly, while those eating too little don’t get enough boost.

Time expansion based on house temp, season, and litter moisture. Ideally, expand before day 5 post-vaccination, getting the brooding area to the size needed by day 20 in one go, adding new litter, and skipping mid-process changes. If insulation makes that challenging, move some old litter to the new pen and mix it with fresh stuff during expansion.

After expanding, make the brooding area as big as possible with thick litter (over 5 cm) so chickens can move around. Mix and dilute oocysts evenly in the litter. This keeps reinfection moderate and uniform, cutting down reactions.

Aim for 55–70% air humidity and 25–30% litter moisture. Proper litter moisture helps oocysts sporulate, but too much speeds it up and boosts rates, causing fast coccidia growth. Some chickens might get bloody stools or die, especially in farms with high wild strain pressure on their first go.

If the litter is dry, spray it lightly to maintain humidity; if it’s too wet, boost ventilation or add fresh litter.

Note: Don’t fully replace litter within 25 days. The vaccine needs fecal contact to keep boosting—chickens must eat oocysts from feces to build strong immunity.

Good litter quality and management are the key to making this vaccine work.